Hint: Denaturation refers to the destruction and disruption of protein structure.

Explanation:

Denaturation of proteins refers to the structural change in a protein due to external factors like temperature and pH, which results in the loss of its biological function. However, denaturation does not break peptide bonds, meaning the primary structure (sequence of amino acids linked by peptide bonds) remains intact. Instead, it disrupts weaker interactions such as hydrogen bonds, hydrophobic interactions, and disulfide linkages, leading to the loss of secondary, tertiary, or quaternary structure.

Thus, while statement 3 is generally true, it is not related to denaturation, making it the incorrect choice in this context.

Thus, statement three is the incorrect statement. In denaturation, protein is not formed.

1. It results due to change of temperature and pH. ✅

Correct: Denaturation occurs when external factors like high temperature, extreme pH, or chemical agents disrupt the weak interactions (hydrogen bonds, ionic bonds, and hydrophobic interactions) that maintain the protein's structure.
Example: Cooking an egg denatures egg white proteins due to heat.

2. It results in the loss of biological activity of proteins. ✅

Correct: The specific three-dimensional shape of a protein is crucial for its function. When denatured, the protein loses its functional shape, making it inactive.
Example: Enzymes lose their catalytic activity when denatured because the active site is altered.

4. Uncoiling of the helical structure takes place. ✅

Correct: Denaturation disrupts the secondary and tertiary structures of proteins, leading to the unfolding of α-helices and β-sheets into a more random coil-like structure.
Example: The helical structure of keratin in hair is altered when exposed to extreme heat or chemicals.

1.	\(e^{-\omega t}\)	2.	\(\text{sin}\omega t\)
3.	\(\text{sin}\omega t+\text{cos}\omega t\)	4.	\(\text{sin}(\omega t+\pi/4)\)

NEET 2022 Exam Paper - Ganganagar